April 21st, 2021, 2:45 PM PDT. [79] In 2020, she was awarded a Guggenheim Fellowship. But this curiosity-driven research led in directions that none of us anticipated at the start of the project.. What if I could become a scientist who worked on discovering things about the natural world, maybe things no one had ever known before?. Along with Berkeley and the chemical company BASF, CARA academic partners include UCLA and Stanford University. May 11, 2015. Doudna and Charpentier began collaborating in 2011. She had blond hair and blue eyes, and she . CRISPR-Cas12a, one of the DNA-cutting proteins revolutionizing biology today, has an unexpected side effect that makes it an ideal enzyme for simple, rapid and accurate disease diagnostics. [5], At Yale, Doudna's group was able to crystallize and solve the three-dimensional structure of the catalytic core of the Tetrahymena Group I ribozyme. She is the president of the Innovative Genomics Institute. EIN: 23-7203666. Doudna was awarded the 2020 Nobel Prize in Chemistry, along with Charpentier, for the development of a method for genome editing, CRISPR-Cas9. A simple, precise and inexpensive method for cutting DNA to insert genes into human cells could transform genetic medicine, making routine what now are expensive, complicated and rare procedures for replacing defective genes in order to fix genetic disease or even cure AIDS. Updated October 8, 2020 The Nobel Prize in Chemistry 2020, Born: 19 February 1964, Washington, D.C., USA, Affiliation at the time of the award: Jennifer Doudna and her team focus on developing novel CRISPR-Cas technologies and using them to study molecular mechanisms of disease. Simon & Schuster, $35. See also:https://innovativegenomics.org, Taiwans top science award, theTang Prize, has gone to two UC Berkeley scientists well-known in the fields of biochemistry and physics: Jennifer Doudna, for her invention of CRISPR-Cas9 gene editing, and Arthur Rosenfeld, often called the godfather of energy efficiency.. [43] In September 2018, the appeals court decided in favor of the Broad Institute's patent. Emmanuelle Charpentier and Jennifer Doudna are awarded the Nobel Prize in Chemistry 2020 for discovering one of gene technology's sharpest tools: the CRISPR/Cas9 genetic scissors. Its the direct result of exceptional scholarship as well as thousands and thousands of donations from our loyal alumni and friends. eingriff in die evolution jennifer a doudna buch jpc. [10][21] Even though Doudna was told that "Women don't go into science," she knew that she wanted to be a scientist no matter what. [74] In 2020, she received the Wolf Prize in Medicine (jointly with Emmanuelle Charpentier). In 2011, Dr. Jennifer Doudna began studying an enzyme called Cas9. By Andrew Pollack. Biochemist Jennifer Doudna and microbiologist Emmanuelle Charpentier co-invented the gene-editing system CRISPR-Cas9, a technology for editing DNA with unprecedented precision and efficiency. On this Wikipedia the language links are at the top of the page across from the article title. [75] Also in 2020, Doudna and Charpentier were awarded the Nobel Prize in Chemistry "for the development of a method for genome editing. [7] She started her first scientific research in the lab of professor Sharon Panasenko. Email [7] This initial work to solve large RNA structures led to further structural studies on an internal ribosome entry site(IRES) and protein-RNA complexes such as the Signal Recognition Particle. 2020 Jun;19(6):380-381. doi: 10.1038/d41573-020-00095-z. ", "Jennifer Doudna (UC Berkeley / HHMI): Genome Engineering with CRISPR-Cas9", "Into the Future with CRISPR Technology with Jennifer Doudna", CRISPR Scientist's Biography Explores Ethics Of Rewriting The Code Of Life, History of the creation-evolution controversy, Relationship between religion and science, Timeline of biology and organic chemistry, The Event Horizon Telescope Collaboration, European Organization for Nuclear Research CERN, Bangladesh Environmental Lawyers Association, Dejusticia: The Center for Law, Justice and Society, https://en.wikipedia.org/w/index.php?title=Jennifer_Doudna&oldid=1141324945, Fellows of the American Academy of Microbiology, Members of the National Academy of Medicine, Members of the Pontifical Academy of Sciences, Members of the United States National Academy of Sciences, University of California, Berkeley College of Letters and Science faculty, University of California, San Francisco faculty, Yale Department of Molecular Biophysics & Biochemistry faculty, Pages containing links to subscription-only content, Short description is different from Wikidata, All Wikipedia articles written in American English, Pages using Template:Post-nominals with customized linking, Articles containing potentially dated statements from 2022, All articles containing potentially dated statements, Nobelprize template using Wikidata property P8024, Interlanguage link template existing link, Creative Commons Attribution-ShareAlike License 3.0, First X-ray based structure of catalytic RNA, This page was last edited on 24 February 2023, at 13:51. ALS Publications by Jennifer Doudna October 8, 2020 This list is a compilation of all publications with 2020 Chemistry Nobel Laureate Jennifer Doudna as co-author which used the resources of the Advanced Light Source. [14] She has been a co-recipient of the Gruber Prize in Genetics (2015),[15] the Tang Prize (2016),[16] the Canada Gairdner International Award (2016),[17] and the Japan Prize (2017). [34][35] Their discovery relies on a protein named Cas9 found in the Streptococcus bacterial "CRISPR" immune system that cooperates with guide RNA and works like scissors. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPRa revolutionary new technology that she helped createto make heritable changes in human embryos. [14] This work is divided into three major areas: the CRISPR system, RNA interference, and translational control via MicroRNAs. Jennifer Doudna. College faculty have been leaders at the frontiers of knowledge since 1872. [80] In 2021, Pope Francis appointed Doudna, and two other female Nobel laureates Donna Strickland and Emmanuelle Charpentier, as members of the Pontifical Academy of Sciences. Studying how bacteria fight viral infections may sound like a niche area of biology, and it was, said Doudna. [14] Doudna also gained access to the synchrotron at Lawrence Berkeley National Laboratory for her experiments with high powered x-ray diffraction. [11], Doudna was a Searle Scholar and received the 1996 Beckman Young Investigators Award. Biochemist Jennifer Doudna and microbiologist Emmanuelle Charpentier co-invented the gene-editing system CRISPR-Cas9, a technology for editing DNA with unprecedented precision and efficiency. eingriff in die evolution von jennifer a doudna samuel h. schpfung 2 0 wie forscher in die evolution eingreifen welt. Before the talkDistillationswriter Meir Rinde sat down with Doudna to find out what scientists can do with CRISPR, whether we should worry about designer embryos, and how to grow 500 tomatoes on a single plant. Jennifer Doudna is a Nobel Laureate in Chemistry, and a Professor of Biochemistry, Biophysics and Structural Biology. Doudna and Charpentier were awarded the Nobel Prize in Chemistry in 2020. This telling of the mystery and discovery of science captured my imagination., 2021 Honorary Doctorate in Science, University of Chicago, 2021 Alma Dea Morani Renaissance Woman Award, the Women in Medicine Legacy Foundation, 2021 Award for Excellence in Molecular Diagnostics, The Association for Molecular Pathology, 2020 Vanderbilt Prize in Biomedical Science, 2020 Wolf Prize in Medicine, The Wolf Foundation, 2019 Microbiology Society Prize Medal, Scotland, 2019 Nierenberg Prize, Scripps Oceanographic Institute, 2019 Lui Che Woo Welfare Betterment Prize, 2019 Honorary Doctorate in Science, Oxford University, 2019 Honorary Doctorate in Science, York University, 2019 Honorary Doctorate in Science, Bates College, 2018 Honorary Doctorate of Science, University of Southern California, 2018 American Cancer Society Medal of Honor, 2018 National Academy of Sciences Award in Chemical Sciences, 2018 Gustavus John Esselen Award for Chemistry, Northeastern Sec Amer Chemical Society, 2018 Lila & Murray Gruber Memorial Cancer Research Award, American Academy of Dermatology, 2018 Dickson Prize in Science, Carnegie Mellon University, 2018 Pearl Meister Greengard Prize, Rockefeller University, 2017 Honorary Doctorate of Science, Hong Kong University, 2017 Honorary Doctorate of Science, Mount Sinai School of Medicine, 2017 George R. Stibitz Computer & Communications Pioneer Award, 2017 The Edward O. Wilson Biodiversity Technology Pioneer Award, 2017 Golden Plate Award, International Achievement Organization, 2017 Wallace H. Coulter Lectureship Award, The American Association for Clinical Chemistry, 2017 BBVA Frontiers of Knowledge Award, Spain, 2017 F.A. 2023 World, Region and Country Top Lists World\'s Top 2% Scientists list 20221.081.124 scientists, 216 country, 19.482 university/institutionNew. Jennifer Doudna, Howard Hughes Investigator and Professor of Biochemistry, Biophysics and Structural Biology at UC Berkeley was recently featured in the Independent for her work on Crispr, which has taken the world of genetics by storm. [42] Feng Zhang at the Broad Institute had shown that CRISPR-Cas9 could edit genes in cultured human cells a few months after Doudna and Charpentier published their method. Her parents as well as her teachers encouraged her curiosity. Our two departments provide fundamental and applied studies of an outstanding caliber. . ", "This court battle will decide who will make a fortune from gene-editing technique", "CRISPR Therapeutics, Intellia Therapeutics, and Caribou Biosciences announce grant of US patent for CRISPR/Cas9 Genome Editing", "Broad Institute takes a hit in European CRISPR patent struggle", "Caribou Biosciences Announces Co-Founding of Intellia Therapeutics", "Intellia Therapeutics Congratulates Co-Founder Jennifer Doudna On Winning the 2020 Nobel Prize in Chemistry for Inventing the Revolutionary CRISPR/Cas9 Genome Editing Technology", "A day with Jennifer Doudna: Trying to keep up with one of the world's most sought-after scientists", "A Crack in Creation review Jennifer Doudna, Crispr and a great scientific breakthrough", "Mammoth Biosciences Closes on Series A Worth $23 Million", "Mammoth Biosciences Raises $45 Million to Build Next Generation CRISPR Products For Therapeutics and Diagnostics", "CRISPR pioneer Doudna opens COVID-19 testing lab BioNews", "Mammoth Biosciences Announces Peer-Reviewed Validation Of Its Rapid, CRISPR-Based COVID-19 Diagnostic", "Beckman Young Investigators Award Recipients", "Gene Editing Pioneers Selected to Receive America's Most Distinguished Prize in Medicine", "Jennifer Doudna To Receive 2018 Pearl Meister Greengard Prize", "Doudna receives Medal of Honor from American Cancer Society", "LUI Che Woo Prize Reveals 2019 Laureates Furthering Its Mission to Enrich World Civilisation", "Nobel Prize Awarded to ASM Members for Development of CRISPR-Cas9", Creative Commons Attribution 4.0 International License, "Royal Society Terms, conditions and policies", "Golden Plate Awardees of the American Academy of Achievement", "Jennifer A. Doudna, Ph.D. For more than a century, these academic institutions have worked independently to select Nobel Prize laureates. Until then, they had been researching different aspects of RNA and CRISPR (an immune system used by bacteria to fend off viruses) independently Doudna at the University of California, Berkeley, and Charpentier at Ume University in Sweden. [26], Doudna was an undergraduate student at Pomona College in Claremont, California, where she studied biochemistry. Biochemist Jennifer Doudna and biophysicist Eva Nogales led an international collaboration with results that point the way to the rational design of new and improved versions of Cas9 enzymes for basic research and genetic engineering. March 9, 2021 Jennifer Doudna, a Nobel Prize recipient for her work on the gene-editing tool CRISPR, and the "life sciences revolution" are the dual subjects of Walter Isaacson's latest. CRISPR-Cas9 allows scientists to rewrite DNA the code of life in any . CAMBRIDGE, Mass., Oct. 07, 2020 (GLOBE NEWSWIRE) -- Today, Jennifer Doudna, Ph.D., one of Intellia Therapeutics, Inc.'s scientific co-founders, was awarded the 2020 Nobel Prize in Chemistry for the development of the CRISPR/Cas9 genome editing technology. UC Berkeley biochemist Jennifer Doudna joined Joseph Biden this morning at the World Economic Forum in Davos, Switzerland, as the vice president promoted a major new U.S. initiative to speed the discovery of cures for cancer. [7] This is analogous, but chemically distinct from, the way proteins typically have a core of hydrophobic amino acids. Please note: The views and opinions expressed in these articles are those of the authors and do not necessarily reflect the official policy or positions of UC Berkeley. [22], In 2017, Doudna co-founded Mammoth Biosciences,[54] a San Francisco-based bioengineering tech startup. Further steps made toward a hyper-accurate gene editor. Doudna was one of the first women to share a Nobel in the sciences. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a method for genome editing. [7] She started this project at the Cech lab in 1991 and finished it at Yale University in 1996. [10][34] Doudna and several other leading biologists called for a worldwide moratorium on any clinical application of gene editing using CRISPR. In this latest "Bloomberg Studio 1.0," host Emily Chang sits down with CRISPR co-inventor and 2020 Nobel Prize winner, Dr. Jennifer Doudna. As scientists race to find new diagnostic tests for the COVID-19 coronavirus. A team of researchers have expanded the role of the newly discovered CRISPR protein C2c2 that targets RNA instead of DNA. [47] In September 2013, Doudna cofounded Editas Medicine with Zhang and others despite their legal battles, but she quit in June 2014; Charpentier then invited her to join CRISPR Therapeutics, but she declined following the "divorce"-like experience at Editas. Photo: Brittany Hosea-Small, Jennifer A. Doudna Sort. Nature built her sense of curiosity and her desire to understand the underlying biological mechanisms of life. [30] She left Genentech after two months and returned to Berkeley with the help of colleague Michael Marletta,[31] cancelling all of her obligations to study CRISPR. Emmanuelle Marie Charpentier (* 11.Dezember 1968 in Juvisy-sur-Orge, Frankreich) ist eine franzsische Mikrobiologin, Genetikerin und Biochemikerin. Developing and applying novel CRISPR-based tools toward applications in biotechnology, diagnostics, neurodegenerative diseases, and other diseases. Jennifer Doudna is a senior investigator at Gladstone Institutes. The discovery of CRISPR-Cas9, made in 2012, provided the foundation for gene editing, enabling . [11] This system was first discovered by Yoshizumi Ishino and colleagues in 1987[36] and later characterized by Francisco Mojica,[37] but Doudna and Emmanuelle Charpentier showed for the first time that they could use different RNAs to program it to cut and edit different DNAs. h-index: 145: 101: i10-index: 366: 322: 0. The pharmaceutical company GlaxoSmithKline (GSK) today announced a five-year collaboration with UC Berkeley and UCSF to establish a laboratory where state-of-the-art CRISPR techniques will be used to explore how gene mutations cause disease, potentially yielding new technologies using CRISPR that would rapidly accelerate the discovery of new medicines. Author Asher Mullard. [34] Before the UC Berkeley patent application was decided, a patent was granted to the Broad investigators and UC Berkeley filed a lawsuit against the decision. 2020 wurde ihr fr die Entwicklung der Genschere" CRISPR/Cas9 zusammen mit Jennifer A. Doudna der Nobelpreis fr Chemie verliehen. [41], The CRISPR system created a new straightforward way to edit DNA and there was a rush to patent the technique. Nobel dl'ne layk grlen en son kadnlar, Edebiyatta Louise Glck, Fizikte Andrea M. Ghez, Kimyada Emmanuelle Charpentier ve Jennifer A. Doudna (2020), Ekonomide Esther Duflo (2019 . With your help we are embarking on many exciting projects here at the College. Bakar Labs, the facilitys flagship life sciences incubator, has been operational since mid-November, offering space to tenant companies. Author details Scopus", "A DAY WITH JENNIFER DOUDNA: TRYING TO KEEP UP WITH ONE OF THE WORLD'S MOST SOUGHT-AFTER SCIENTISTS", Jill Banfield: How a curious Google search led me to Jennifer Doudna, Jennifer Doudna's First Reactions to 2020 Nobel Prize Win, "The CRISPR Pioneers: Their Breakthrough Work Could Change the World", "A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity", "Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product", "CRISPR co-inventor Jennifer Doudna talks ethics and biological frontiers", "Scientists Seek Ban on Method of Editing the Human Genome", "Biotechnology. warum macht sex spa die evolution der menschlichen. Faced with such slow progress, he chose to study the proteins in photosynthetic bacteria instead. All rights reserved. This is no accident. As a young student, my father got me a copy of the book, The Double Helixby James Watson. Doudna went to the lab of Thomas Cech at the University of Colorado Boulder to crystallize and determine the three-dimensional structure of a ribozyme for the first time, so ribozyme structure could be compared with that of Enzymes, the catalytic Proteins. Jennifer Doudna Nat Rev Drug Discov. Jennifer Doudna. Professor of Molecular and Cell Biology and Chemistry, UC Berkeley. "[4][3], She was elected to the National Academy of Sciences in 2002,[7] the American Academy of Arts and Sciences in 2003, the National Academy of Medicine in 2010 and the National Academy of Inventors in 2014. [53] This work could lead to new drugs to stop infections without causing harm to the tissues of the body. Two UC Berkeley scientists, Jennifer Doudna and John Ngai, each will receive a $100,000 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation to explore innovative research that could impact global health. She has also received many other prizes for her discoveries, including the Japan Prize (2016), the Kavli Prize (2018), and the LUI Che Woo Welfare Betterment Prize (2019). [67] In 2018, Doudna was awarded the NAS Award in Chemical Sciences,[68] the Pearl Meister Greengard Prize from the Rockefeller University,[69] and a Medal of Honor from the American Cancer Society. In 10 years, CRISPR transformed medicine. Wed. 1 Mar 2023. Jeff Akst, (2018) "The higher court's decision to uphold the ruling of the Patent Trial and Appeal Board essentially ends the intellectual property battle in theUS", "How CRISPR lets us edit our DNA". Jennifer Doudna and Radiolab can explain, UC Berkeleys Jennifer Doudna wins 2020 Nobel Prize in Chemistry, UC Berkeley launches trial of saliva test for COVID-19, Scientists pivot to COVID-19 research, hoping for quick results to deal with pandemic, Campus lab takes COVID-19 testing to utility workers, underserved, UC Berkeley scientists spin up a robotic COVID-19 testing lab, Jennifer Doudna awarded 2020 Wolf Prize in Medicine, UC rings out 2019 with its 20th CRISPR patent, UC now holds largest CRISPR-Cas9 patent portfolio, University of California awarded 15th U.S. CRISPR-Cas9 patent, UC receives its 11th U.S. patent for CRISPR-Cas9, Doudna awarded prize for helping build a better, more harmonious world, Newly granted CRISPR patents boost UCs U.S. portfolio to 10, Eighth CRISPR patent issued by U.S.; seven more soon to come, GlaxoSmithKline taps UCs CRISPR expertise to speed drug discovery, UC receives patent for use of CRISPR-Cas9 to tune gene expression, Introducing a kinder, gentler way to blow holes in cells, UC awarded third CRISPR patent, expanding its gene-editing portfolio, U.S. patent office indicates it will issue third CRISPR patent to UC, Patent awarded for DNA-targeting complex at heart of CRISPR-Cas9 gene editing, Doudna receives Medal of Honor from American Cancer Society, CRISPR scissors, Cas12a, enables cutting-edge diagnostics, Discovery helps engineer more accurate Cas9s for CRISPR editing, Researchers discover how CRISPR proteins find their target, Defense department pours $65 million into making CRISPR safer, Anti-CRISPR proteins decrease off-target side effects of CRISPR-Cas9, European Patent Office to grant UC a broad patent on CRISPR-Cas9, Doudna awarded Japan Prize for invention of CRISPR gene editing, CRISPR research institute expands into agriculture, microbiology, CRISPR toolbox expanded by protein that cuts RNA in two distinct ways, UC Berkeley to partner in $600M Chan Zuckerberg science Biohub, Taiwans Tang Prizes awarded to Doudna, Rosenfeld, Doudna named foreign member of UKs Royal Society, Doudna joins Biden in Davos rollout of cancer moonshot, CRISPR-Cas9 gene editing: check three times, cut once, Unlocking the Key to Immunological Memory in Bacteria, Jennifer Doudna, Saul Perlmutter named 2015 Breakthrough Prize winners, Jennifer Doudna featured on NPR's Morning Edition for her work on CRISPR/Cas9 a tool for editing genes, College of Chemistry launches research hub with BASF, UCLA and Stanford, Jennifer Doudna receives Lurie Award for gene editing breakthrough, New insight into an emerging genome-editing tool, Puzzling question in bacterial immune system answered, Science magazine calls Berkeley discoveries top breakthroughs of 2013, Biochemist Jennifer Doudna hailed for discovery of holy grail of genetic engineering, Cheap and easy technique to snip DNA could revolutionize gene therapy, Pilot program to bolster biophysical sciences innovation pipeline, Gates foundation awards $100,000 grants for novel global health research, Berkeley Research Infrastructure Commons (RIC), http://mcb.berkeley.edu/faculty/BMB/doudnaj.html, Life Sciences Intellectual Property Review. [11], As CRISPR becomes increasingly used to edit multicellular organisms, Doudna continues to be called upon to serve as a thought-leader on the ethics of changing an organism's function using CRISPR technology. The remarkable breadth and depth of resources available to our students readies them as chemists and chemical engineers to address societys most urgent 21st-century issues. [7] While in the Szostak lab, Doudna re-engineered the self-splicing Tetrahymena Group I catalytic intron into a true catalytic ribozyme that copied RNA templates. Senior Investigator, Gladstone Institutes, Investigator, Howard Hughes Medical Institute, Professor, Molecular and Cell Biology and Chemistry, UC Berkeley, Li Ka Shing Chancellors Chair in Biomedical and Health Sciences, UC Berkeley, Faculty Scientist, Physical Biosciences Division, Lawrence Berkeley National Laboratory. In addition to her scientific . [62][63] In 2000, she was awarded the Alan T. Waterman Award, the National Science Foundation's highest honor that annually recognizes an outstanding researcher under the age of 35, for her structure determination of a ribozyme. UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH). Thanks to a rapid funding program thrown together by wealthy entrepreneurs barely six weeks ago, seven COVID-19 research projects at the University of California, Berkeley, are getting an infusion of cash $2.2 million in all that could turn up new diagnostics and potential treatments for the infection within months. leserforum wiener zeitung online. Nobel Prize Outreach. Articles Cited by Public access. Jennifer A. Doudna, Ph.D Yale Medicine Magazine, 1999 - Spring Jennifer A. Doudna, Ph.D., professor of molecular biophysics and biochemistry and assistant investigator at the Howard Hughes Medical Institute, was one of 17 researchers honored by the National Academy of Sciences. Dr. Doudna shared the award with her research collaborator, Dr. Emmanuelle Charpentier.This is the first time two women scientists have . [21][23][24][25] A visiting lecturer on cancer cells further encouraged her pursuit of science as a career choice. [7][10] However, her French teacher suggested she stick with science. The life processes of organisms are controlled by genes made up of sections of DNA. She is also the Li Ka Shing Chancellors Chair and a professor in the Departments of Chemistry and of Molecular and Cell Biology at UC Berkeley, as well as an investigator of the Howard Hughes Medical Institute. University of California, Berkeley, biochemist Jennifer Doudna today won the 2020 Nobel Prize in Chemistry, sharing it with colleague Emmanuelle Charpentier for the co-development of CRISPR-Cas9, a genome editing breakthrough that has revolutionized biomedicine. She received her bachelors degree in biochemistry in 1985 from Pomona College, and her doctorate in biological chemistry and molecular pharmacology in 1989 from Harvard Medical School. Copyright UC Regents. Jennifer A. Doudna | Molecular and Cell Biology Home Faculty and Research Faculty by Name Jennifer A. Doudna Jennifer A. Doudna Howard Hughes Medical Institute Investigator, Li Ka Shing Chancellor's Chair in Biomedical and Health Sciences and Professor of Biochemistry, Biophysics and Structural Biology Lab Homepage: http://rna.berkeley.edu/ The U.S. Patent and Trademark Office has issued a notice of allowance for a University of California patent application covering systems and methods for using single molecule guide RNAs that, when combined with the Cas9 protein, create more efficient and effective ways for scientists to target and edit genes. Jennifer A. Doudna and Samuel H. Sternberg. Jennifer Anne Doudna ForMemRS ( / dadn /; [1] born February 19, 1964) [2] is an American biochemist who has done pioneering work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. [57] This center processes more than 1,000 patient samples per day. 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